Johnny Wise | Food Toxicology | Innovative Research Award

Innovative Research Award

Johnny Wise
Affiliation The University of Toledo
Country United States
Scopus ID 57204262821
Documents 40
Citations 989
h-index 15
Subject Area Food Toxicology and Risk Assessment
Event International Food Scientist Awards
ORCID 0000-0002-9416-8570

Johnny Wise
The University of Toledo, United States

Johnny Wise is a researcher whose scholarly activities focus on food toxicology, environmental exposure science, neurotoxicology, and risk assessment. His published work investigates the biological effects of environmental contaminants, particularly hexavalent chromium (Cr(VI)), emphasizing neurological outcomes, essential metal homeostasis, and dietary interactions relevant to public health. The combination of peer-reviewed publications, measurable citation impact, and interdisciplinary research contributes to his academic profile within food safety and toxicological sciences.[1]

Abstract

This academic recognition profile summarizes the research achievements of Johnny Wise in food toxicology and environmental health sciences. His work examines toxic metal exposure, behavioral toxicology, dietary influences on toxic responses, and mechanisms of essential metal dysregulation. Publications demonstrate continued investigation into chromium toxicology using experimental animal models, providing evidence relevant to environmental risk assessment and food safety. Citation metrics and publication output indicate sustained scholarly engagement within the field.[1][2]

Keywords

Food Toxicology, Risk Assessment, Hexavalent Chromium, Neurobehavioral Toxicology, Environmental Health, Essential Metal Homeostasis, High-Fat Diet, Food Safety

Introduction

Food toxicology integrates toxicological science, nutrition, and environmental exposure assessment to evaluate contaminants capable of affecting human and animal health. Johnny Wise has contributed to this discipline through investigations into chromium exposure, dietary interactions, and neurological responses in laboratory models. These studies assist in understanding biological mechanisms that may influence toxicological risk evaluations and regulatory decision-making.[2][3]

Research Profile

The research profile reflects interdisciplinary expertise spanning toxicology, neuroscience, food safety, environmental health, and analytical biology. According to the provided bibliometric indicators, the researcher has produced 40 indexed publications, received 989 citations, and achieved an h-index of 15. These metrics demonstrate measurable scholarly visibility while illustrating continued contributions to environmental toxicology and food-related health research.[1]

Research Contributions

  • Investigated neurobehavioral consequences of chronic low-level Cr(VI) exposure.
  • Studied interactions between high-fat diets and environmental toxicants.
  • Examined chromium accumulation in brain tissues and age-dependent biological responses.
  • Evaluated essential metal dyshomeostasis associated with toxic metal exposure.
  • Contributed evidence supporting food toxicology and environmental risk assessment.

Publications

  1. Neurobehavioral Responses of Rats Exposed to Low-Concentration Hexavalent Chromium [Cr(VI)] in Drinking Water Combined with a High-Fat Diet. Applied Sciences (2026). DOI: 10.3390/app16157367.
  2. Hexavalent Chromium Oropharyngeal Aspiration Induced Behavior Effects and Essential Metal Dyshomeostasis in Young Hartley Guinea Pigs. Applied Sciences (2025). DOI: 10.3390/app16010059.
  3. Chromium Selectively Accumulates in the Rat Hippocampus after 90 Days of Exposure to Cr(VI) in Drinking Water and Induces Age- and Sex-Dependent Metal Dyshomeostasis. Toxics (2024). DOI: 10.3390/toxics12100722.

Research Impact

The documented citation record, publication output, and subject specialization indicate consistent participation in environmental toxicology research. The cited studies contribute experimental evidence concerning chromium exposure, behavioral outcomes, and biological mechanisms that may support future toxicological evaluations and food safety investigations. The research also demonstrates interdisciplinary collaboration between toxicology, nutrition, and neuroscience.[1][2]

Award Suitability

Based on the supplied bibliometric indicators and recent peer-reviewed publications, Johnny Wise demonstrates qualifications consistent with consideration for the International Food Scientist Awards under an Innovative Research Award category. The research portfolio reflects sustained scholarly productivity, multidisciplinary investigation, and contributions to food toxicology and environmental health using recognized scientific methodologies. This assessment is based on documented academic outputs rather than subjective evaluation.[1][2]

Conclusion

Johnny Wise has established a research profile centered on toxicological mechanisms associated with environmental contaminants and their implications for food safety and public health. Through experimental investigations of chromium exposure and biological responses, the published work contributes to ongoing scientific understanding in food toxicology, risk assessment, and environmental health sciences while providing evidence suitable for scholarly recognition within international research communities.[3]

References

  1. Elsevier. (n.d.). Scopus Author Details: Johnny Wise, Author ID 57204262821. Scopus.
    https://www.scopus.com/authid/detail.uri?authorId=57204262821
  2. ORCID. (n.d.). Johnny Wise โ€“ ORCID Record.ย 
    https://orcid.org/0000-0002-9416-8570
  3. Wise, J., et al. (2026). Neurobehavioral Responses of Rats Exposed to Low-Concentration Hexavalent Chromium [Cr(VI)] in Drinking Water Combined with a High-Fat Diet. Applied Sciences, 16(15), 7367. DOI:ย https://doi.org/10.3390/app16157367
  4. Wise, J., et al. (2025). Hexavalent Chromium Oropharyngeal Aspiration Induced Behavior Effects and Essential Metal Dyshomeostasis in Young Hartley Guinea Pigs. Applied Sciences, 16(1), 59. DOI:ย https://doi.org/10.3390/app16010059
  5. Wise, J., et al. (2024). Chromium Selectively Accumulates in the Rat Hippocampus after 90 Days of Exposure to Cr(VI) in Drinking Water and Induces Age- and Sex-Dependent Metal Dyshomeostasis. Toxics, 12(10), 722. DOI:ย https://doi.org/10.3390/toxics12100722

Joao Lago | Pharmacology | Best Researcher Award

Prof Dr. Joao Lago | Pharmacology | Best Researcher Awardย 

Professor at Federal University of ABC, Brazil

Prof. Dr. Joao Henrique Ghilardi Lago is a distinguished researcher in Chemistry, specializing in the Chemistry of Natural Products. With extensive academic credentials including a Ph.D. from the University of Sรฃo Paulo and a background in both chemical education and research, he has made significant contributions to the field. His current position at the Federal University of ABC reflects his commitment to teaching and research in biosystems and organic chemistry. ๐ŸŒฟ๐Ÿ”ฌ Dr. Lago’s work is marked by his leadership in various research projects focusing on the characterization and potential applications of specialized metabolites from Brazilian flora, particularly in combating neglected tropical diseases. His role as a grantee and reviewer for multiple scientific funding agencies underscores his influence and expertise in the scientific community, contributing to the advancement of bioorganic chemistry and pharmaceutical research in Brazil and beyond. ๐ŸŒ

Professional Profile:

Education

Prof. Dr. Joao Henrique Ghilardi Lago pursued a rigorous academic journey culminating in his esteemed position in the scientific community. He earned his Bachelor’s degree in Chemistry from the Federal University of Mato Grosso do Sul (UFMS), Brazil, before advancing to achieve a Master’s and Ph.D. in Chemistry from the University of Sรฃo Paulo (USP), one of Brazil’s leading institutions. ๐ŸŽ“ His doctoral research focused on natural products chemistry, a field he has since dedicated himself to with passion and expertise. Througho ut his educational path, Dr. Lago has demonstrated a commitment to excellence in scientific inquiry and a deep understanding of organic chemistry principles. His academic background has equipped him with the skills and knowledge to lead impactful research initiatives, particularly in the chemistry of natural products and their potential applications in medicine and pharmacology. ๐ŸŒฟ๐Ÿ”ฌ

Professional Experience

Prof. Dr. Joao Henrique Ghilardi Lago boasts a rich professional experience marked by significant contributions to the fields of chemistry and academia. He has held key positions such as a researcher and professor at the Federal University of Mato Grosso do Sul (UFMS), Brazil, where he has actively engaged in teaching and mentoring students while conducting groundbreaking research. ๐ŸŒŸ Dr. Lago’s research interests encompass natural products chemistry, medicinal chemistry, and synthetic organic chemistry, areas in which he has published numerous influential papers in prestigious scientific journals. His professional journey also includes collaborations with national and international research groups, fostering interdisciplinary approaches to tackle complex scientific challenges. As a recognized expert in his field, Dr. Lago continues to inspire and educate future generations of scientists through his dedicated work and leadership in academia. ๐Ÿ”๐Ÿ”ฌ

Research Interest

Prof. Dr. Joao Henrique Ghilardi Lago’s research interests are centered around the fascinating realms of natural products chemistry, medicinal chemistry, and synthetic organic chemistry. ๐ŸŒฟ His work delves into the exploration and synthesis of bioactive compounds derived from natural sources, aiming to uncover their potential applications in medicine and related fields. Dr. Lago is particularly intrigued by the molecular structures of natural products and their intricate biological activities, seeking to elucidate mechanisms that could lead to the development of new therapeutic agents. His research encompasses a blend of innovative synthetic methodologies and biological evaluations, striving to bridge

Award and Honor

Prof. Dr. Joao Henrique Ghilardi Lago has received numerous awards and honors throughout his distinguished career, recognizing his outstanding contributions to the field of organic and medicinal chemistry. ๐Ÿ† His accolades highlight his exceptional research achievements, including prestigious fellowships and grants that have supported his innovative investigations in natural products chemistry and drug discovery. Dr. Lago’s work has been consistently recognized for its impact on advancing scientific knowledge and addressing critical challenges in pharmaceutical science. His dedication to excellence and pioneering research methodologies has earned him the respect of his peers and the admiration of the scientific community. These honors underscore Dr. Lago’s significant role in shaping the future of chemical research and his ongoing commitment to excellence in academia and beyond. ๐ŸŒŸ

Research Skills

Prof. Dr. Joao Henrique Ghilardi Lago is highly skilled in conducting rigorous and innovative research, showcasing a profound expertise in organic synthesis, natural products chemistry, and medicinal chemistry. ๐Ÿงช His research skills encompass the design and execution of complex synthetic pathways to access novel compounds of biological interest. Dr. Lago excels in applying state-of-the-art analytical techniques to characterize and elucidate the structures of synthesized molecules, ensuring precision and accuracy in his findings. His proficiency extends to conducting biological evaluations to assess the pharmacological potential and mechanisms of action of synthesized compounds, contributing to the advancement of drug discovery and development. Dr. Lago’s research prowess is underscored by his ability to integrate diverse scientific disciplines, fostering collaborations that enrich the scope and impact of his investigations. With a commitment to excellence and innovation, he continues to push the boundaries of chemical research, making significant contributions to the field. ๐ŸŒŸ

Publications

๐Ÿ“š2012

  • Title: The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-part II
  • Journal: Current Medicinal Chemistry
  • Citation: 375
  • Authors: TJ Schmidt, SA Khalid, รJ Romanha, TMA Alves, MW Biavatti, R Brun, …

๐Ÿ“š2004

  • Title: Benzoic Acid Derivatives from Piper Species and Their Fungitoxic Activity against Cladosporium cladosporioides and C. sphaerospermum
  • Journal: Journal of Natural Products
  • Citation: 271
  • Authors: JHG Lago, CS Ramos, DCC Casanova, AA Morandim, DCB Bergamo, …

๐Ÿ“š2015

  • Title: Antimicrobial activity of oleanolic and ursolic acids: an update
  • Journal: Evidence-Based Complementary and Alternative Medicine
  • Citation: 249
  • Authors: JA Jesus, JHG Lago, MD Laurenti, ES Yamamoto, LFD Passero

๐Ÿ“š2011

  • Title: ฮฑ-Pinene isolated from Schinus terebinthifolius Raddi (Anacardiaceae) induces apoptosis and confers antimetastatic protection in a melanoma model
  • Journal: Biochemical and Biophysical Research Communications
  • Citation: 234
  • Authors: AL Matsuo, CR Figueiredo, DC Arruda, FV Pereira, JAB Scutti, …

๐Ÿ“š2014

  • Title: Structure-activity association of flavonoids in lung diseases
  • Journal: Molecules
  • Citation: 218
  • Authors: JHG Lago, AC Toledo-Arruda, M Mernak, KH Barrosa, MA Martins, …

๐Ÿ“š2012

  • Title: The Genus Caesalpinia L. (Caesalpiniaceae): Phytochemical and Pharmacological Characteristics
  • Journal: Molecules
  • Citation: 175
  • Authors: JLB Zanin, BA De Carvalho, P Salles Martineli, MH Dos Santos, …

๐Ÿ“š2003

  • Title: Antifungal flavanones and prenylated hydroquinones from Piper crassinervium Kunth
  • Journal: Phytochemistry
  • Citation: 171
  • Authors: AP Danelutte, JHG Lago, MCM Young, MJ Kato

๐Ÿ“š2004

  • Title: Evaluation of a methylation procedure to determine cyclopropenoids fatty acids from Sterculia striata St. Hil. Et Nauds seed oil
  • Journal: Journal of Chromatography A
  • Citation: 143
  • Authors: S Aued-Pimentel, JHG Lago, MH Chaves, EE Kumagai

๐Ÿ“š2003

  • Title: Trypanocidal tetrahydrofuran lignans from inflorescences of Piper solmsianum
  • Journal: Phytochemistry
  • Citation: 138
  • Authors: RCC Martins, JHG Lago, S Albuquerque, MJ Kato

๐Ÿ“š2012

  • Title: In vitro antileishmanial and antitrypanosomal activities of flavanones from Baccharis retusa DC.(Asteraceae)
  • Journal: Experimental Parasitology
  • Citation: 132
  • Authors: SS Grecco, JQ Reimรฃo, AG Tempone, P Sartorelli, RLOR Cunha, …

๐Ÿ“š2007

  • Title: Constituintes fenรณlicos polares de Schinus terebinthifolius Raddi (Anacardiaceae)
  • Journal: Quรญmica Nova
  • Citation: 117
  • Authors: M Ceruks, P Romoff, OA Fรกvero, JHG Lago

๐Ÿ“š2015

  • Title: Camphene isolated from essential oil of Piper cernuum (Piperaceae) induces intrinsic apoptosis in melanoma cells and displays antitumor activity in vivo
  • Journal: Biochemical and Biophysical Research Communications
  • Citation: 107
  • Authors: N Girola, CR Figueiredo, CF Farias, RA Azevedo, AK Ferreira, SF Teixeira, …

๐Ÿ“š2013

  • Title: Flavonone treatment reverses airway inflammation and remodeling in an asthma murine model
  • Journal: British Journal of Pharmacology
  • Citation: 106
  • Authors: AC Toledo, CPP Sakoda, A Perini, NM Pinheiro, RM Magalhaes, …

๐Ÿ“š2006

  • Title: Chromenes from Peperomia serpens (Sw.) Loudon (Piperaceae)
  • Journal: Phytochemistry
  • Citation: 105
  • Authors: ROS Kitamura, P Romoff, MCM Young, MJ Kato, JHG Lago

๐Ÿ“š2013

  • Title: Chemical Composition and Cytotoxicity Evaluation of Essential Oil from Leaves of Casearia Sylvestris, Its Main Compound ฮฑ-Zingiberene and Derivatives
  • Journal: Molecules
  • Citation: 101
  • Authors: DD Bou, JHG Lago, CR Figueiredo, AL Matsuo, RC Guadagnin, …

๐Ÿ“š2006

  • Title: Antioxidant activity of prenylated hydroquinone and benzoic acid derivatives from Piper crassinervium Kunth
  • Journal: Phytochemistry
  • Citation: 99
  • Authors: LF Yamaguchi, JHG Lago, TM Tanizaki, P Di Mascio, MJ Kato

๐Ÿ“š2003

  • Title: Antifungal aromadendrane sesquiterpenoids from the leaves of Xylopia brasiliensis
  • Journal: Journal of the Brazilian Chemical Society
  • Citation: 91
  • Authors: IC Moreira, JHG Lago, MCM Young, NF Roque

๐Ÿ“š2011

  • Title: Chemical and Biological Evaluation of Essential Oils from Two Species of Myrtaceae โ€” Eugenia uniflora L. and Plinia trunciflora (O. Berg) Kausel
  • Journal: Molecules
  • Citation: 87
  • Authors: JHG Lago, ED Souza, B Mariane, R Pascon, MA Vallim, RCC Martins, …

๐Ÿ“š2012

  • Title: Essential oils from Schinus terebinthifolius leaves โ€“ chemical composition and in vitro cytotoxicity evaluation
  • Journal: Pharmaceutical Biology
  • Citation: 86
  • Authors: JS Santana, P Sartorelli, RC Guadagnin, AL Matsuo, CR Figueiredo, …

๐Ÿ“š2016

  • Title: Evidences of herbal medicineโ€derived natural products effects in inflammatory lung diseases
  • Journal: Mediators of Inflammation
  • Citation: 82
  • Authors: FPR Santana, NM Pinheiro, MIB Mernak, RF Righetti, MA Martins, …

๐Ÿ“š2002

  • Title: Terpenoids from Guarea guidonia
  • Journal: Phytochemistry
  • Citation: 80
  • Authors: JHG Lago, CB Brochini, NF Roque

๐Ÿ“š2016

  • Title: Isololiolide, a carotenoid metabolite isolated from the brown alga Cystoseira tamariscifolia, is cytotoxic and able to induce apoptosis in hepatocarcinoma cells through caspase โ€ฆ
  • Journal: Phytomedicine
  • Citation: 78
  • Authors: C Vizetto-Duarte, L Custรณdio, KN Gangadhar, JHG Lago, C Dias, …

๐Ÿ“š2015

  • Title: The Effect of Ursolic Acid on Leishmania (Leishmania) amazonensis Is Related to Programmed Cell Death and Presents Therapeutic Potential in Experimental โ€ฆ
  • Journal: PLoS One
  • Citation: 78
  • Authors: ES Yamamoto, BLS Campos, JA Jesus, MD Laurenti, SP Ribeiro, …

๐Ÿ“š2012

  • Title: Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo
  • Journal: PLoS One
  • Citation: 76
  • Authors: MH Massaoka, AL Matsuo, CR Figueiredo, CF Farias, N Girola, …