Pintu Kumar Mandal | Carbohydrate chemistry | Best Researcher Award

Dr. Pintu Kumar Mandal | Carbohydrate chemistry | Best Researcher Award

CSIR-Central Drug Research Institute, India

 Dr. Pintu Kumar Mandal is currently a Principal Scientist at CSIR‑Central Drug Research Institute (CSIR‑CDRI) in Lucknow, within the Medicinal and Process Chemistry Division. With a strong foundation in synthetic carbohydrate chemistry, Dr. Mandal has spearheaded numerous national and in-house research projects, including enzyme-mimicking bifunctional catalysts, stereoselective glycosylation strategies, and anti‑filarial agent development against Brugia malayi. Alongside his academic leadership, he has mentored a thriving research group comprising seven current PhD candidates and one project associate, with six PhD graduates now holding prestigious positions worldwide—from Harvard Medical School to government and industrial posts. Before joining CSIR‑CDRI, he held research positions in the UK and the USA as a Newton International Fellow at Leeds and a Research Scientist at Georgia State University. He has earned recognition such as the Newton Fellowship and the Association of Carbohydrate Chemists & Technologists (India) C.G. Merchant Memorial Award‑2023 for excellence in synthetic carbohydrate chemistry.

Profile

Scholar

🎓Education :

Dr. Mandal earned his B.Sc. (Hons.) in Chemistry with first‑class honors from Midnapore College under Vidyasagar University in 2003, followed by an M.Sc. in Organic Chemistry (first class) from Vidyasagar University in 2005. He pursued a Ph.D. in Synthetic Carbohydrate Chemistry at Bose Institute (affiliated with Jadavpur University), Kolkata, under the mentorship of Prof. Anup Kumar Misra. His doctoral thesis, completed in 2009, was titled “Synthesis of Oligosaccharides of Biological Importance,” focusing on the development of oligosaccharide building blocks relevant to biological systems. This rigorous training laid the groundwork for Dr. Mandal’s future research contributions, equipping him with expertise in organic synthesis, carbohydrate functionalization, and glycosylation strategies, which have been pivotal throughout his academic and scientific career.

💼Experience :

Dr. Mandal has accumulated substantial experience since the completion of his Ph.D. in 2009. From 2009 to 2011, he was a Newton International Fellow at the University of Leeds, UK, focusing on advanced carbohydrate synthesis. He then moved to Georgia State University, USA (2011–2013), as a Research Scientist, further refining his expertise in glycosylation and catalytic processes. In 2013, he joined CSIR‑CDRI in Lucknow as a Senior Scientist, rising to Principal Scientist in 2017 within the Medicinal and Process Chemistry Division. He has led and co-led multiple funded projects from DST‑SERB and CSIR‑CDRI, tackling stereoselective synthesis, enzyme-like catalysis, drug repurposing for infectious diseases, anti‑filarial drug development, and pan‑cancer research. His professional journey spans international research fellowships and leadership roles in national laboratories, highlighting his evolution from post‑doctoral chemist to established principal investigator.

🏆Awards and Honors :

Dr. Mandal earned the prestigious Newton International Fellowship (Royal Society) for his post‑doctoral research at the University of Leeds (2009–2011), recognizing his early contributions to carbohydrate chemistry. More recently, in 2023 he received the C.G. Merchant Memorial Award from the Association of Carbohydrate Chemists & Technologists (India), acknowledging his outstanding accomplishments in synthetic carbohydrate chemistry. These honors underscore his sustained impact and leadership in the field, celebrating both his innovative academic research and his contributions to the scientific community in India and abroad.

🔬Research Focus :

Dr. Mandal’s research concentrates on synthetic carbohydrate chemistry and the development of stereoselective glycosylation methodologies. His work includes metal‑catalyzed C–H glycosylation and multi‑component strategies to construct bioactive C‑ and N‑glycoside scaffolds. He leads projects on enzyme‑like small‑molecule catalysts for stereoselective glycosylation and cooperative dual‑activation catalysis. Central to his studies are applications in drug discovery: remote biomolecule functionalization, anti‑filarial agents (targeting Brugia malayi trehalose 6‑phosphate phosphatase), and drug repurposing initiatives for COVID‑19, JE, SARS, parasitic and microbial diseases, as well as pan‑cancer therapy. His group’s goal is to harness carbohydrate-based structures for biologically relevant interventions and to pioneer novel synthetic strategies that have real-world medicinal applications.

Conclusion

Dr. Mandal exemplifies what the Best Researcher Award seeks: high-impact scientific contributions, consistent funding, effective leadership, and recognized excellence. His research into stereoselective glycosylation has significantly advanced medicinal chemistry and carbohydrate synthesis. To further strengthen his candidature, diversifying interdisciplinary collaborations, strengthening translational pathways (patents/industry), and engaging broader audiences would elevate both scientific influence and societal impact. Overall, he stands as a compelling nominee—already excellent, with clear room to grow into an even more influential scientist.

Publication   :          

Title: HDAC as onco target: Reviewing the synthetic approaches with SAR study of their inhibitors
Authors: R Sangwan, R Rajan, PK Mandal
Year: 2018
Citations: 91

Title: Recent advances in photoinduced glycosylation: oligosaccharides, glycoconjugates and their synthetic applications
Authors: R Sangwan, PK Mandal
Year: 2017
Citations: 52

Title: Towards a structural basis for the relationship between blood group and the severity of El Tor cholera
Authors: PK Mandal, TR Branson, ED Hayes, JF Ross, JA Gavín, AH Daranas, …
Year: 2012
Citations: 50

Title: An Overview on the Chemical N‐Functionalization of Sugars and Formation of N‐Glycosides
Authors: R Sangwan, A Khanam, PK Mandal
Year: 2020
Citations: 40

Title: Mechanistic studies on a sulfoxide transfer reaction mediated by diphenyl sulfoxide/triflic anhydride
Authors: MA Fascione, SJ Adshead, PK Mandal, CA Kilner, AG Leach, WB Turnbull
Year: 2012
Citations: 36

Title: Tris(pentafluorophenyl)borane-Catalyzed Stereoselective C-Glycosylation of Indoles with Glycosyl Trichloroacetimidates: Access to 3-Indolyl-C-glycosides
Authors: A Dubey, A Tiwari, PK Mandal
Year: 2021
Citations: 30

Title: HClO4-SiO2 catalyzed multicomponent reactions for the synthesis of privileged heterocyclic structures
Authors: PK Mandal, AK Misra
Year: 2006
Citations: 28

Title: Substituted hydrazinecarbothioamide as potent antitubercular agents: synthesis and quantitative structure–activity relationship (QSAR)
Authors: S Singh, PK Mandal, N Singh, AK Misra, S Singh, V Chaturvedi, S Sinha, …
Year: 2010
Citations: 27

Title: Recent Advances and Development in Visible‐Light‐Mediated Glycosylation: An Expanding Research Area in Glycochemistry
Authors: Z Azeem, P Kumar Mandal
Year: 2023
Citations: 26

Title: Organocatalytic [3+2] Cycloadditions: Toward Facile Synthesis of Sulfonyl‐1,2,3‐Triazolyl and Fully Substituted 1,2,3‐Triazolyl Glycoconjugates
Authors: R Sangwan, Javed, A Dubey, PK Mandal
Year: 2017
Citations: 26

Mei luo | Organic and organometallic chemistry | Best Researcher Award

Prof. Mei luo | Organic and organometallic chemistry | Best Researcher Award

Professor at Hefei university of technology, China 

Dr. Mei Luo is currently serving as an Associate Professor at Hefei University of Technology, bringing a wealth of experience in organic and organometallic chemistry. She obtained her Ph.D. from the University of Science and Technology of China and pursued postdoctoral research at prestigious institutions such as Peking University, the University of Utah, and the University of North Carolina at Chapel Hill. With a strong focus on synthesizing chiral organometallic complexes and drug synthesis, Dr. Luo has contributed significantly to the field through innovative research and academic endeavors.

Author Metrics

Scopus Profile

ORCID Profile

Dr. Mei Luo has achieved notable recognition in academia, boasting over 200 patents since 2006. Her research has been extensively published in reputable journals, highlighting her impact in the areas of metal complex synthesis, characterization, and their applications in medicinal chemistry and catalysis. Her publications reflect a strong interdisciplinary approach, integrating theoretical and experimental methodologies to advance the understanding and application of organometallic chemistry.

Dr. Mei Luo, currently affiliated with Hefei University of Technology in Hefei, China, has a notable academic profile. According to Scopus Author Identifier, her research has garnered 248 citations from 224 documents, with an h-index of 9. She has authored 62 documents indexed in Scopus, reflecting her significant contributions to the field of organic and organometallic chemistry. For more detailed metrics and information, accessing her full profile via Scopus or ORCID would provide comprehensive insights into her research impact and academic achievements.

Education

Dr. Luo earned her M.S. in Chemistry from Hefei University of Technology and completed her Ph.D. at the University of Science and Technology of China. Her academic journey also includes postdoctoral fellowships at Peking University, the University of Utah, and the University of North Carolina at Chapel Hill, where she further honed her expertise in organic and organometallic chemistry.

Research Focus

Dr. Mei Luo’s research primarily revolves around the synthesis of chiral organometallic complexes and drug synthesis. She has made significant contributions to understanding the structural and functional properties of metal complexes, particularly their applications in medicinal chemistry, catalysis, and molecular docking studies.

Professional Journey

Beginning with her educational background, Dr. Luo’s professional journey spans multiple prestigious institutions and positions. After completing her Ph.D., she conducted postdoctoral research at Peking University, the University of Utah, and the University of North Carolina at Chapel Hill. Currently, she serves as an Associate Professor at Hefei University of Technology, where she continues to lead research and mentor students in organic and organometallic chemistry.

Honors & Awards

Dr. Mei Luo has received recognition for her contributions to organic and organometallic chemistry, although specific awards and honors were not detailed in the provided information. Her extensive publication record and patent portfolio underscore her achievements and impact within her field of expertise.

Publications Noted & Contributions

Dr. Luo has authored numerous influential publications, focusing on metal complexes with biological applications. Notable publications include studies on the synthesis, characterization, and biological activities of Zn (II), Cu (II), Co (II), and Ni (II) complexes bearing aza-heterocyclic ligands, as well as their antitumor effects. Her research contributions extend to structural investigations, Hirshfeld surface analyses, and quantum mechanical studies of various organometallic compounds.

Mei Luo has authored several notable books and publications, including:

Zn (II), Cu (II), Co (II), and Ni (II) complexes bearing aza-heterocyclic ligands: synthesis, characterization, and anticancer activities

  • Journal: Journal of the Iranian Chemical Society
  • Date: 2024-06
  • DOI: 10.1007/s13738-024-03021-x
  • Contributors: Amir Nazeer, Qasim Umar, Yanting Yang, Mei Luo

A Brief Review: Advancement in the Synthesis of Amine through the Leuckart Reaction

Synthesis, characterization and anticancer activities of Zn2+, Cu2+, Co2+ and Ni2+ complexes involving chiral amino alcohols

  • Journal: RSC Advances
  • Date: 2022
  • DOI: 10.1039/D2RA05576G
  • Contributors: Qasim Umar, Y. H. Huang, Amir Nazeer, Hao Yin, Jing Cheng Zhang, Mei Luo, X. G. Meng

Correction to: One-step templated synthesis of chiral organometallic salicyloxazoline complexes

  • Journal: BMC Chemistry
  • Date: 2019-05-10
  • DOI: 10.1186/s13065-019-0577-8
  • Contributors: Mei Luo, Jing Cheng Zhang, Hao Yin, Cheng Ming Wang, Susan Morris-Natschke, Kuo-Hsiung Lee

One-step templated synthesis of chiral organometallic salicyloxazoline complexes

  • Journal: BMC Chemistry
  • Date: 2019-04-04
  • DOI: 10.1186/s13065-019-0565-z
  • Contributors: Mei Luo, Jing Cheng Zhang, Hao Yin, Cheng Ming Wang, Susan Morris-Natschke, Kuo-Hsiung Le

Research Timeline

Dr. Mei Luo’s research journey began with her doctoral studies at the University of Science and Technology of China, followed by postdoctoral research positions at Peking University, the University of Utah, and the University of North Carolina at Chapel Hill. Since joining Hefei University of Technology as an Associate Professor, she has continued to expand her research focus on chiral organometallic complex synthesis and drug synthesis, publishing extensively in respected scientific journals.

2024:

  1. Zn (II), Cu (II), Co (II), and Ni (II) complexes bearing aza-heterocyclic ligands: synthesis, characterization, and anticancer activities
    • This study focused on synthesizing and characterizing metal complexes with aza-heterocyclic ligands. It explored their potential anticancer activities, contributing to the field of medicinal chemistry and organometallic complexes.

2023:

  1. 一Research progress on one-pot synthesis of oxazoline metal complexes
    • This publication (translated as “Progress in One-Pot Synthesis of Oxazoline Metal Complexes”) discussed advancements in the one-pot synthesis method for creating oxazoline metal complexes, emphasizing efficiency and innovation in synthetic organic chemistry.
  2. Combining Effect of Zn2+, Cu2+, Co2+, and Ni2+ Complexes Containing Chiral Amino Alcohols: Synthesis, Characterization and their Anticancer Activities
    • This research delved into the synthesis and characterization of metal complexes containing chiral amino alcohols. It investigated their combined effects and anticancer activities, contributing valuable insights into the potential therapeutic applications of these complexes.

These recent achievements highlight Mei Luo’s ongoing contributions to the fields of organic synthesis, organometallic chemistry, and medicinal chemistry, particularly focusing on innovative synthesis methods and the development of compounds with significant biological activities.

Collaborations and Projects

Dr. Luo actively collaborates with researchers both nationally and internationally, enhancing her research impact and fostering interdisciplinary approaches in organic and organometallic chemistry. Her collaborations encompass projects that explore novel synthesis methodologies, structural characterization techniques, and the biological applications of metal complexes, contributing to advancements in medicinal chemistry and catalysis.