Dr. Ola Ahmed Saleh is a distinguished professor at the Medicinal and Pharmaceutical Chemistry Department, National Research Centre, Cairo, Egypt. With extensive experience in pharmaceutical chemistry, she specializes in the synthesis of active pharmaceutical entities and the chiral separation of racemic drugs.
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Dr. Saleh’s research contributions have garnered significant recognition in the academic community, reflected in numerous citations and the impact of her work on pharmaceutical chemistry. Her publications are frequently referenced, underscoring her influence in the field.
- Citations: 170 citations from 161 documents
- Publications: 21 documents
- h-index: 8
Education
Dr. Saleh holds a Bachelor’s degree in Pharmacy, followed by a Master’s and PhD in Pharmaceutical Chemistry. Her advanced degrees underscore her deep knowledge and expertise in her specialized field of study.
Research Focus
Dr. Saleh’s research focuses on synthesizing biologically active pharmaceutical entities. She has a particular interest in chiral separation and analyzing racemic drugs using high-performance liquid chromatography (HPLC), aiming to improve the efficacy and safety of pharmaceutical compounds.
Professional Journey
Dr. Saleh has a distinguished professional career marked by significant contributions to pharmaceutical chemistry. Her work spans various aspects of drug synthesis and analytical methods, establishing her as a leading figure in her field.
Honors & Awards
Throughout her career, Dr. Saleh has received numerous honors and awards, recognizing her exceptional contributions to pharmaceutical chemistry. These accolades highlight her dedication to research and her impact on the scientific community.
Publications Noted & Contributions
Dr. Saleh has an extensive publication record, with notable works in prestigious journals. Her research includes the synthesis of novel pharmaceutical compounds and the development of validated methods for drug analysis, contributing valuable knowledge to the field of pharmaceutical chemistry.
Title: A validated chromatographic method for simultaneous determination of guaifenesin enantiomers and ambroxol HCl in pharmaceutical formulation
- Journal: RSC Advances
- Year: 2015
- DOI: 10.1039/c5ra19391e
- EID: 2-s2.0-84946595298
- Contributors: Saleh, O.A.; Yehia, A.M.; Abd-El Sattar El-Azzouny, A.; Aboul-Enein, H.Y.
Title: Synthesis and Anticonvulsant Activity of Substituted-1,3-diazaspiro[4.5]decan-4-ones
- Journal: Archiv der Pharmazie
- Year: 2015
- DOI: 10.1002/ardp.201500092
- EID: 2-s2.0-84938418531
- Contributors: Aboul-Enein, M.N.; El-Azzouny, A.A.S.; Saleh, O.A.; Amin, K.M.; Maklad, Y.A.; Hassan, R.M.
Title: A validated high performance liquid chromatographic (HPLC) assay for nitazoxanide in bulk and in pharmaceutical formulations
- Journal: Current Pharmaceutical Analysis
- Year: 2014
- DOI: 10.2174/1573412910666140506225012
- EID: 2-s2.0-84904730253
- Contributors: Saleh, O.A.; El-Azzouny, A.A.; Aboul-Enein, H.Y.; Badawey, A.M.
Title: Analysis of Stiripentol Enantiomers on Several Chiral Stationary Phases: A Comparative Study
- Journal: Chromatographia
- Year: 2014
- DOI: 10.1007/s10337-014-2818-2
- EID: 2-s2.0-84925489270
- Contributors: Saleh, O.A.; El-Behairy, M.F.; Badawey, A.M.; El-Azzouny, A.A.; Aboul-Enein, H.Y.
Title: Riluzole: Validation of stability-indicating HPLC, D1 and DD1 spectrophotometric assays
- Journal: Journal of Chromatographic Science
- Year: 2014
- DOI: 10.1093/chromsci/bmt062
- EID: 2-s2.0-84902196955
- Contributors: Saleh, O.A.; El-Azzouny, A.A.; Aboul-Enein, H.Y.; Badawey, A.M.
Research Timeline
Dr. Saleh’s research timeline spans over two decades, beginning in the late 1990s. Her sustained research efforts have continuously advanced the understanding of drug synthesis and analysis, contributing to the ongoing development of pharmaceutical science.
Collaborations and Projects
Dr. Saleh has collaborated extensively with researchers both locally and internationally. Her projects often involve interdisciplinary approaches, combining synthetic chemistry with advanced analytical techniques to address complex challenges in pharmaceutical research.
Recognition of Expertise in Analytical Chemistry
Dr. Ola Ahmed Saleh has been awarded the Analytical Chemistry Award in recognition of her outstanding contributions to the field. Her expertise spans various aspects of analytical chemistry, including method development, validation, and application in pharmaceutical analysis. Her work is distinguished by its rigorous approach to separation science, particularly in the enantioseparation of pharmaceutical compounds using advanced HPLC techniques.
Contributions to Method Development and Validation
Dr. Saleh’s research has significantly advanced the field through the development and validation of novel analytical methods. Notably, she has pioneered stability-indicating HPLC assays for a range of pharmaceutical compounds, ensuring accurate and reliable determination of drug purity and stability. Her methods have been widely adopted and cited in the scientific community, demonstrating their robustness and applicability in pharmaceutical quality control.
Impact on Pharmaceutical Analysis
Her work on enantioseparation using chiral stationary phases has provided critical insights into the stereochemical properties of drugs, influencing pharmacokinetic studies and therapeutic efficacy assessments. These contributions have enhanced our understanding of drug interactions and metabolism, crucial for optimizing drug formulations and patient outcomes.
Innovation in Chromatographic Techniques
Dr. Saleh’s innovative approaches in chromatographic techniques have been pivotal in addressing complex analytical challenges, such as simultaneous determination of multiple enantiomers and structurally similar compounds. Her research integrates experimental design optimization with computational modeling, pushing the boundaries of analytical chemistry capabilities.
Future Directions and Research Impact
Continuing her research trajectory, Dr. Saleh aims to explore new frontiers in analytical chemistry, particularly in green analytical methods and molecular docking studies. These efforts promise to advance sustainable analytical practices and deepen our understanding of molecular interactions in drug development.