David Nwikwe | Toxicology | Best Researcher Award

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Dr. David Nwikwe | Toxicology | Best Researcher Award

Lecturer, Kings University, Nigeria

πŸ‘¨β€πŸ« David Chukwuma Nwikwe, PhD is a dedicated biochemist, educator, and researcher with expertise in molecular biology, toxicology, and medicinal biochemistry. He currently serves as a Lecturer at Kings University, Nigeria, and a Volunteer Instructor at the University of the People, USA. With a strong passion for research, he has contributed significantly to scientific knowledge, publishing extensively in peer-reviewed journals. Beyond academia, he has worked on numerous community development projects, focusing on public health advocacy, malaria control, and reproductive health. His leadership and research efforts have earned him several prestigious awards.

Publications Profile

Education πŸŽ“

  • Ph.D. Biochemistry – University of Ilorin (2022)
  • M.Sc. Biochemistry – University of Ilorin (2016)
  • B.Sc. Biochemistry – University of Ilorin (2013)
  • National Diploma in Science Laboratory Technology – Kwara State Polytechnic (2009)
  • Senior School Certificate – Okesuna High School, Lagos (2005)
  • Primary School Leaving Certificate – Ade-Oshodi Memorial Baptist Primary School, Lagos (1999)

Experience πŸ’Ό

  • Lecturer, Kings University, Nigeria (2023–Present) – Teaching, supervising research, and department coordination.
  • Volunteer Instructor, University of the People, USA (2023–Present) – Online course facilitation and student guidance.
  • Lecturer II, Crown-Hill University, Nigeria (2022–2023) – Teaching and examination officer duties.
  • Teaching Assistant, University of Ilorin (2017–2018) – Guided undergraduate students.
  • Research Assistant, University of Ilorin (2017–2023) – Coordinated over 50 B.Sc. & M.Sc. students.
  • Program Officer, WOYODEV NGO (2017–2021) – Led community health initiatives.

Honors & Awards πŸ†

  • Outstanding PhD Graduate Award, University of Ilorin (2023)
  • Best Student (Zonal Secondary School Category), Spelling Bee (2005)
  • Class Representative, M.Sc. & National Diploma (2014-2016, 2007-2009)
  • Senior Prefect & Class Monitor, Okesuna High School (2004-2005)
  • Certificate of Honor, Nigerian Christian Corpers’ Fellowship (2014)

Research Focus πŸ”¬

Dr. Nwikwe’s research revolves around biochemical toxicology, medicinal plant extracts, molecular biology, and oxidative stress. His work evaluates antioxidant, anti-inflammatory, and hepatoprotective potentials of natural compounds. He has explored antimalarial and anticancer properties of bioactive compounds and assessed the toxicity of synthetic drugs. His studies on oxidative stress, metabolic disorders, and neurodegeneration contribute to disease prevention strategies. His research significantly advances phytomedicine, drug safety, and biochemical pharmacology.

Publications πŸ“š

  • Assessment of Hepatotoxicity Effects of Long-Term Administration of SynriamTM in Rats
  • Toxicological Assessment of ZnO-Vernonia amygdalina Nanoparticle-Treated Asa River Water in Albino Rats
  • Antioxidant and Anti-Inflammatory Potentials of Methanol Extract of Syzygium aromaticum L. Flower Buds on Formalin-Induced Paw Oedema in Rats
  • Effects of Stress on Cognitive Performance
  • Study on Antimalarial Activity of Capsicum frutescens L. Fruit Extracts During Early and Established Plasmodium Infection in Mice
  • Evaluation of Cryptolepis sanguinolenta Stem Ethanol Extract in Animal Models
  • Assessing the Oxidative Stress Reducing Potential of Spilanthes filicaulis (Schumach & Thonn) Ethyl-Acetate Sub-fractions on Plasmodium berghei Infected Mice

Joao Lago | Pharmacology | Best Researcher Award

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Prof Dr. Joao Lago | Pharmacology | Best Researcher AwardΒ 

Professor at Federal University of ABC, Brazil

Prof. Dr. Joao Henrique Ghilardi Lago is a distinguished researcher in Chemistry, specializing in the Chemistry of Natural Products. With extensive academic credentials including a Ph.D. from the University of SΓ£o Paulo and a background in both chemical education and research, he has made significant contributions to the field. His current position at the Federal University of ABC reflects his commitment to teaching and research in biosystems and organic chemistry. πŸŒΏπŸ”¬ Dr. Lago’s work is marked by his leadership in various research projects focusing on the characterization and potential applications of specialized metabolites from Brazilian flora, particularly in combating neglected tropical diseases. His role as a grantee and reviewer for multiple scientific funding agencies underscores his influence and expertise in the scientific community, contributing to the advancement of bioorganic chemistry and pharmaceutical research in Brazil and beyond. 🌍

Professional Profile:

Education

Prof. Dr. Joao Henrique Ghilardi Lago pursued a rigorous academic journey culminating in his esteemed position in the scientific community. He earned his Bachelor’s degree in Chemistry from the Federal University of Mato Grosso do Sul (UFMS), Brazil, before advancing to achieve a Master’s and Ph.D. in Chemistry from the University of SΓ£o Paulo (USP), one of Brazil’s leading institutions. πŸŽ“ His doctoral research focused on natural products chemistry, a field he has since dedicated himself to with passion and expertise. Througho ut his educational path, Dr. Lago has demonstrated a commitment to excellence in scientific inquiry and a deep understanding of organic chemistry principles. His academic background has equipped him with the skills and knowledge to lead impactful research initiatives, particularly in the chemistry of natural products and their potential applications in medicine and pharmacology. πŸŒΏπŸ”¬

Professional Experience

Prof. Dr. Joao Henrique Ghilardi Lago boasts a rich professional experience marked by significant contributions to the fields of chemistry and academia. He has held key positions such as a researcher and professor at the Federal University of Mato Grosso do Sul (UFMS), Brazil, where he has actively engaged in teaching and mentoring students while conducting groundbreaking research. 🌟 Dr. Lago’s research interests encompass natural products chemistry, medicinal chemistry, and synthetic organic chemistry, areas in which he has published numerous influential papers in prestigious scientific journals. His professional journey also includes collaborations with national and international research groups, fostering interdisciplinary approaches to tackle complex scientific challenges. As a recognized expert in his field, Dr. Lago continues to inspire and educate future generations of scientists through his dedicated work and leadership in academia. πŸ”πŸ”¬

Research Interest

Prof. Dr. Joao Henrique Ghilardi Lago’s research interests are centered around the fascinating realms of natural products chemistry, medicinal chemistry, and synthetic organic chemistry. 🌿 His work delves into the exploration and synthesis of bioactive compounds derived from natural sources, aiming to uncover their potential applications in medicine and related fields. Dr. Lago is particularly intrigued by the molecular structures of natural products and their intricate biological activities, seeking to elucidate mechanisms that could lead to the development of new therapeutic agents. His research encompasses a blend of innovative synthetic methodologies and biological evaluations, striving to bridge

Award and Honor

Prof. Dr. Joao Henrique Ghilardi Lago has received numerous awards and honors throughout his distinguished career, recognizing his outstanding contributions to the field of organic and medicinal chemistry. πŸ† His accolades highlight his exceptional research achievements, including prestigious fellowships and grants that have supported his innovative investigations in natural products chemistry and drug discovery. Dr. Lago’s work has been consistently recognized for its impact on advancing scientific knowledge and addressing critical challenges in pharmaceutical science. His dedication to excellence and pioneering research methodologies has earned him the respect of his peers and the admiration of the scientific community. These honors underscore Dr. Lago’s significant role in shaping the future of chemical research and his ongoing commitment to excellence in academia and beyond. 🌟

Research Skills

Prof. Dr. Joao Henrique Ghilardi Lago is highly skilled in conducting rigorous and innovative research, showcasing a profound expertise in organic synthesis, natural products chemistry, and medicinal chemistry. πŸ§ͺ His research skills encompass the design and execution of complex synthetic pathways to access novel compounds of biological interest. Dr. Lago excels in applying state-of-the-art analytical techniques to characterize and elucidate the structures of synthesized molecules, ensuring precision and accuracy in his findings. His proficiency extends to conducting biological evaluations to assess the pharmacological potential and mechanisms of action of synthesized compounds, contributing to the advancement of drug discovery and development. Dr. Lago’s research prowess is underscored by his ability to integrate diverse scientific disciplines, fostering collaborations that enrich the scope and impact of his investigations. With a commitment to excellence and innovation, he continues to push the boundaries of chemical research, making significant contributions to the field. 🌟

Publications

πŸ“š2012

  • Title: The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-part II
  • Journal: Current Medicinal Chemistry
  • Citation: 375
  • Authors: TJ Schmidt, SA Khalid, ÁJ Romanha, TMA Alves, MW Biavatti, R Brun, …

πŸ“š2004

  • Title: Benzoic Acid Derivatives from Piper Species and Their Fungitoxic Activity against Cladosporium cladosporioides and C. sphaerospermum
  • Journal: Journal of Natural Products
  • Citation: 271
  • Authors: JHG Lago, CS Ramos, DCC Casanova, AA Morandim, DCB Bergamo, …

πŸ“š2015

  • Title: Antimicrobial activity of oleanolic and ursolic acids: an update
  • Journal: Evidence-Based Complementary and Alternative Medicine
  • Citation: 249
  • Authors: JA Jesus, JHG Lago, MD Laurenti, ES Yamamoto, LFD Passero

πŸ“š2011

  • Title: Ξ±-Pinene isolated from Schinus terebinthifolius Raddi (Anacardiaceae) induces apoptosis and confers antimetastatic protection in a melanoma model
  • Journal: Biochemical and Biophysical Research Communications
  • Citation: 234
  • Authors: AL Matsuo, CR Figueiredo, DC Arruda, FV Pereira, JAB Scutti, …

πŸ“š2014

  • Title: Structure-activity association of flavonoids in lung diseases
  • Journal: Molecules
  • Citation: 218
  • Authors: JHG Lago, AC Toledo-Arruda, M Mernak, KH Barrosa, MA Martins, …

πŸ“š2012

  • Title: The Genus Caesalpinia L. (Caesalpiniaceae): Phytochemical and Pharmacological Characteristics
  • Journal: Molecules
  • Citation: 175
  • Authors: JLB Zanin, BA De Carvalho, P Salles Martineli, MH Dos Santos, …

πŸ“š2003

  • Title: Antifungal flavanones and prenylated hydroquinones from Piper crassinervium Kunth
  • Journal: Phytochemistry
  • Citation: 171
  • Authors: AP Danelutte, JHG Lago, MCM Young, MJ Kato

πŸ“š2004

  • Title: Evaluation of a methylation procedure to determine cyclopropenoids fatty acids from Sterculia striata St. Hil. Et Nauds seed oil
  • Journal: Journal of Chromatography A
  • Citation: 143
  • Authors: S Aued-Pimentel, JHG Lago, MH Chaves, EE Kumagai

πŸ“š2003

  • Title: Trypanocidal tetrahydrofuran lignans from inflorescences of Piper solmsianum
  • Journal: Phytochemistry
  • Citation: 138
  • Authors: RCC Martins, JHG Lago, S Albuquerque, MJ Kato

πŸ“š2012

  • Title: In vitro antileishmanial and antitrypanosomal activities of flavanones from Baccharis retusa DC.(Asteraceae)
  • Journal: Experimental Parasitology
  • Citation: 132
  • Authors: SS Grecco, JQ ReimΓ£o, AG Tempone, P Sartorelli, RLOR Cunha, …

πŸ“š2007

  • Title: Constituintes fenΓ³licos polares de Schinus terebinthifolius Raddi (Anacardiaceae)
  • Journal: QuΓ­mica Nova
  • Citation: 117
  • Authors: M Ceruks, P Romoff, OA FΓ‘vero, JHG Lago

πŸ“š2015

  • Title: Camphene isolated from essential oil of Piper cernuum (Piperaceae) induces intrinsic apoptosis in melanoma cells and displays antitumor activity in vivo
  • Journal: Biochemical and Biophysical Research Communications
  • Citation: 107
  • Authors: N Girola, CR Figueiredo, CF Farias, RA Azevedo, AK Ferreira, SF Teixeira, …

πŸ“š2013

  • Title: Flavonone treatment reverses airway inflammation and remodeling in an asthma murine model
  • Journal: British Journal of Pharmacology
  • Citation: 106
  • Authors: AC Toledo, CPP Sakoda, A Perini, NM Pinheiro, RM Magalhaes, …

πŸ“š2006

  • Title: Chromenes from Peperomia serpens (Sw.) Loudon (Piperaceae)
  • Journal: Phytochemistry
  • Citation: 105
  • Authors: ROS Kitamura, P Romoff, MCM Young, MJ Kato, JHG Lago

πŸ“š2013

  • Title: Chemical Composition and Cytotoxicity Evaluation of Essential Oil from Leaves of Casearia Sylvestris, Its Main Compound Ξ±-Zingiberene and Derivatives
  • Journal: Molecules
  • Citation: 101
  • Authors: DD Bou, JHG Lago, CR Figueiredo, AL Matsuo, RC Guadagnin, …

πŸ“š2006

  • Title: Antioxidant activity of prenylated hydroquinone and benzoic acid derivatives from Piper crassinervium Kunth
  • Journal: Phytochemistry
  • Citation: 99
  • Authors: LF Yamaguchi, JHG Lago, TM Tanizaki, P Di Mascio, MJ Kato

πŸ“š2003

  • Title: Antifungal aromadendrane sesquiterpenoids from the leaves of Xylopia brasiliensis
  • Journal: Journal of the Brazilian Chemical Society
  • Citation: 91
  • Authors: IC Moreira, JHG Lago, MCM Young, NF Roque

πŸ“š2011

  • Title: Chemical and Biological Evaluation of Essential Oils from Two Species of Myrtaceae β€” Eugenia uniflora L. and Plinia trunciflora (O. Berg) Kausel
  • Journal: Molecules
  • Citation: 87
  • Authors: JHG Lago, ED Souza, B Mariane, R Pascon, MA Vallim, RCC Martins, …

πŸ“š2012

  • Title: Essential oils from Schinus terebinthifolius leaves – chemical composition and in vitro cytotoxicity evaluation
  • Journal: Pharmaceutical Biology
  • Citation: 86
  • Authors: JS Santana, P Sartorelli, RC Guadagnin, AL Matsuo, CR Figueiredo, …

πŸ“š2016

  • Title: Evidences of herbal medicine‐derived natural products effects in inflammatory lung diseases
  • Journal: Mediators of Inflammation
  • Citation: 82
  • Authors: FPR Santana, NM Pinheiro, MIB Mernak, RF Righetti, MA Martins, …

πŸ“š2002

  • Title: Terpenoids from Guarea guidonia
  • Journal: Phytochemistry
  • Citation: 80
  • Authors: JHG Lago, CB Brochini, NF Roque

πŸ“š2016

  • Title: Isololiolide, a carotenoid metabolite isolated from the brown alga Cystoseira tamariscifolia, is cytotoxic and able to induce apoptosis in hepatocarcinoma cells through caspase …
  • Journal: Phytomedicine
  • Citation: 78
  • Authors: C Vizetto-Duarte, L CustΓ³dio, KN Gangadhar, JHG Lago, C Dias, …

πŸ“š2015

  • Title: The Effect of Ursolic Acid on Leishmania (Leishmania) amazonensis Is Related to Programmed Cell Death and Presents Therapeutic Potential in Experimental …
  • Journal: PLoS One
  • Citation: 78
  • Authors: ES Yamamoto, BLS Campos, JA Jesus, MD Laurenti, SP Ribeiro, …

πŸ“š2012

  • Title: Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo
  • Journal: PLoS One
  • Citation: 76
  • Authors: MH Massaoka, AL Matsuo, CR Figueiredo, CF Farias, N Girola, …