Chinthakunta NagaRaju | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

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Dr. Chinthakunta NagaRaju | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

 Assistant Professor at Yogivemana University, India

Dr. Chinthakunta Nagaraju is a dedicated researcher and educator in the field of biochemistry, holding a Ph.D., M. Phil., and M.Sc. from Sri Krishnadevaraya University. His academic journey includes significant contributions to molecular biology and bioinformatics, focusing particularly on cancer research. As an Assistant Professor and HOD at PVKK P.G College and currently serving as an Academic Consultant at Yogivemana University, he has enriched his students’ learning through hands-on experience in cell culture, biochemical analysis, and advanced computational techniques like docking and homology modeling. Dr. Nagaraju’s research on ferulic acid analogs and their role in inhibiting protein-protein interactions in cancer cells underscores his commitment to advancing therapeutic strategies. His multifaceted expertise and mentorship in guiding projects related to enzyme modeling, drug screening, and therapeutic agent development highlight his proactive approach in academia and research. 🎓🔬

Professional Profile:

Education🎓

Dr. Chinthakunta Nagaraju’s educational journey in biochemistry reflects a deep commitment to academic excellence and research advancement. He completed his Ph.D. in Biochemistry from Sri Krishnadevaraya University, where his doctoral thesis focused on evaluating ferulic acid analogs as inhibitors of MDM2-p53 protein-protein interactions in cancer cell lines. Prior to his Ph.D., he earned an M. Phil. in Biochemistry, conducting research on homology modeling and virtual screening with natural compounds targeting cancer-related receptors. His academic foundation includes an M.Sc. in Bio-Chemistry and a B.Sc. in Bio-Technology from the same university, demonstrating a progressive trajectory in biological sciences. Dr. Nagaraju’s interdisciplinary approach, blending bioinformatics, molecular biology, and therapeutic research, underscores his comprehensive grasp of biochemical principles and their practical applications in combating cancer. 🎓🔬

 

Professional Experience 📚

Dr. Chinthakunta Nagaraju brings a wealth of professional experience in biochemistry and academia, combining research excellence with teaching leadership. He served as an Assistant Professor and Head of the Department of Biochemistry at PVKK P.G College from August 2018 to August 2022, where he played a pivotal role in curriculum development and student mentorship. Currently, as an Academic Consultant at Yogivemana University since September 2022, Dr. Nagaraju continues to impart his expertise in cell culture techniques, immunological assays, and bioinformatics applications such as docking and molecular dynamics simulations. His tenure has been marked by a commitment to advancing scientific knowledge and fostering a research-intensive environment. Dr. Nagaraju’s contributions extend beyond the classroom, encompassing guided research projects aimed at understanding molecular mechanisms in cancer biology and developing novel therapeutic strategies. 🌱🔬

Research Interest 🔍

Dr. Chinthakunta Nagaraju’s research interests revolve around molecular biology and bioinformatics applications in cancer research. He is particularly focused on exploring the therapeutic potential of natural compounds and their derivatives, with a specific emphasis on targeting key protein interactions involved in cancer progression. His work includes molecular modeling, virtual screening, and computational analysis to identify novel drug candidates that can disrupt critical pathways in cancer cells. Dr. Nagaraju is driven by a passion for understanding the underlying molecular mechanisms of disease and translating his findings into clinical applications that could potentially enhance cancer treatment strategies. His interdisciplinary approach integrates biochemistry, pharmacology, and computational biology to advance precision medicine and personalized therapies. 🧬💻

Award and Honor🏆

Dr. Chinthakunta Nagaraju has been recognized for his outstanding contributions in biochemistry and cancer research through several awards and honors. His dedication to advancing scientific knowledge is exemplified by prestigious accolades acknowledging his research excellence and academic achievements. These awards underscore his significant impact in the field, particularly his work on molecular evaluations of ferulic acid analogs as potential inhibitors of critical protein interactions in cancer cells. Dr. Nagaraju’s commitment to innovative research methodologies, including bioinformatics and computational biology, has earned him respect among peers and recognition within the scientific community. His awards reflect not only his scientific prowess but also his leadership and commitment to advancing biomedical science for the betterment of human health. 🏆🔬

 

Research Skills🌟

Dr. Chinthakunta Nagaraju possesses robust research skills that encompass a blend of experimental techniques and computational methodologies in biochemistry. With expertise in cell culture techniques, he adeptly handles cell maintenance, passage, and preservation, crucial for studying biological processes and drug responses in controlled environments. His proficiency extends to immunological and biochemical analytical techniques, enabling precise characterization and quantification of biomolecules and cellular interactions. Additionally, Dr. Nagaraju has advanced skills in bioinformatics, including molecular modeling, docking studies, and dynamics simulations, which he applies to predict molecular interactions and design novel therapeutic agents. His ability to integrate experimental data with computational analyses enhances his research insights into molecular pathways implicated in cancer and other diseases, driving forward innovative approaches in biomedical research. 🧫🔬

 

Publications📖📚

Comparative binding studies of curcumin and tangeretin on up-stream elements of NF-kB cascade: a combined molecular docking approach

  • Authors: Cheemanapalli, S., Chinthakunta, N., Shaikh, N.M., Pamuru, R.R., Chitta, S.K.
  • Journal: Network Modeling Analysis in Health Informatics and Bioinformatics, 2019, 8(1), 15
  • Citations: 13

A new insight into identification of in silico analysis of natural compounds targeting GPR120

  • Authors: Chinthakunta, N., Cheemanapalli, S., Chinthakunta, S., Anuradha, C.M., Chitta, S.K.
  • Journal: Network Modeling Analysis in Health Informatics and Bioinformatics, 2018, 7(1), 8
  • Citations: 17

Cardioprotective effect of Phyllanthus amarus against high fructose diet induced myocardial and aortic stress in rat model

  • Authors: Putakala, M., Gujjala, S., Nukala, S., Chintakunta, N., Desireddy, S.
  • Journal: Biomedicine and Pharmacotherapy, 2017, 95, pp. 1359–1368
  • Citations: 14

Experimental and molecular docking investigation on DNA interaction of N-substituted phthalimides: antibacterial, antioxidant and hemolytic activities

  • Authors: Nayab, P.S., Irfan, M., Abid, M., Chinta, S.K., Rahisuddin
  • Journal: Luminescence, 2017, 32(3), pp. 298–308
  • Citations: 18

Behzad Shareghi | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

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Prof Behzad Shareghi | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Academic Staff of Shahrekord University, Iran 

Prof. Behzad Shareghi is a distinguished figure in the field of biochemistry, renowned for his contributions to protein stability and enzyme kinetics. Currently serving as a Professor of Biochemistry in the Department of Biology at Shahrekord University, Iran, Prof. Shareghi has garnered extensive recognition for his expertise and scholarly achievements. With a solid educational background, including a Ph.D. in Biochemistry from the University of Tehran, he brings a wealth of knowledge and experience to his academic pursuits. Prof. Shareghi’s research interests primarily revolve around exploring the thermodynamic aspects of protein denaturation, aiming to unravel the intricate relationship between protein structure and function. His investigations encompass various denaturation methods, ranging from thermal and chemical denaturation to solvent and salt denaturation, as well as the interaction of proteins with surfactants. Through his meticulous approach and utilization of advanced spectroscopic techniques, such as UV–vis spectroscopy, thermal stability, fluorescence spectroscopy, and circular dichroism spectroscopy, Prof. Shareghi seeks to deepen our understanding of fundamental biological processes at the molecular level.

Professional Profile:

Education

Prof. Behzad Shareghi has pursued an extensive academic journey, culminating in a strong foundation in biochemistry. He obtained his Ph.D. in Biochemistry from the University of Tehran, Iran, in 1996, following a Master’s degree in Biochemistry from the same institution in 1991. Prior to his postgraduate studies, Prof. Shareghi earned his Bachelor’s degree in Chemistry from the University of Isfahan, Iran, in 1987. His academic background reflects a deep commitment to advancing knowledge in biochemistry, laying the groundwork for his subsequent contributions to the field through research, teaching, and scholarly activities.

 

Professional Experience

Prof. Behzad Shareghi brings a wealth of professional experience to his role as a Professor of Biochemistry in the Department of Biology at the Faculty of Science, Shahrekord University, Iran. With an illustrious career spanning several decades, Prof. Shareghi has established himself as a distinguished academician and researcher in the field of protein stability and enzyme kinetics. He has held various academic positions, contributing significantly to the advancement of scientific knowledge and the training of future scientists. Prof. Shareghi’s expertise extends beyond academia, as evidenced by his active involvement in research projects, scientific collaborations, and scholarly publications. His leadership and mentorship have inspired countless students and colleagues, fostering a culture of excellence and innovation in biochemical research. Through his professional endeavors, Prof. Shareghi continues to make meaningful contributions to the scientific community while shaping the next generation of scientists in Iran and beyond.

Research Interest

Prof. Behzad Shareghi’s research interests are centered around the thermodynamic aspects of protein denaturation and enzyme kinetics. His work delves into unraveling the intricate relationship between protein structure and function by investigating various denaturation methods, including thermal, chemical, solvent, and salt denaturation, along with the interaction of proteins with surfactants. Prof. Shareghi employs advanced spectroscopic techniques such as UV–vis spectroscopy, thermal stability, fluorescence spectroscopy, and circular dichroism spectroscopy to study protein stability. Additionally, he focuses on elucidating the kinetics of enzyme activation and inactivation when exposed to different ligands, such as inhibitors, activators, and denaturants. Through his research, Prof. Shareghi aims to provide valuable insights into fundamental biological processes, contributing to the advancement of biochemistry and molecular biology.

Award and Honor

Prof. Behzad Shareghi has been recognized and honored for his outstanding contributions to the field of biochemistry and scientific research. Throughout his illustrious career, he has received numerous accolades and awards that reflect his dedication, expertise, and impactful work in protein stability and enzyme kinetics. These accolades serve as a testament to Prof. Shareghi’s exemplary achievements and his significant contributions to advancing our understanding of protein structure-function relationships. His awards not only recognize his individual accomplishments but also underscore his broader impact on the scientific community and his commitment to excellence in research and academia. Prof. Shareghi’s accolades highlight his standing as a distinguished scholar and leader in the field of biochemistry, inspiring others with his passion for scientific discovery and innovation.

 

Research Skills

Prof. Behzad Shareghi possesses exceptional research skills honed through years of dedicated academic inquiry and scientific investigation. With a strong foundation in biochemistry and protein stability, he demonstrates proficiency in designing and executing complex experiments aimed at elucidating the thermodynamic aspects of protein denaturation and enzyme kinetics. Prof. Shareghi is adept at employing a wide range of research methodologies, including spectroscopic techniques such as UV–vis spectroscopy, fluorescence spectroscopy, and circular dichroism spectroscopy, to probe protein structure-function relationships. His keen analytical abilities enable him to interpret experimental data effectively, drawing meaningful conclusions that advance our understanding of fundamental biological processes. Additionally, Prof. Shareghi demonstrates a meticulous approach to experimental design and execution, ensuring the reliability and reproducibility of his findings. Overall, his research skills position him as a leading authority in the field of biochemistry, contributing significantly to scientific knowledge and innovation.

Publications

  • Multi-spectroscopic and molecular modeling studies of interaction between two different angiotensin I converting enzyme inhibitory peptides from gluten hydrolysate and human …
    • Author: R Assaran Darban, B Shareghi, A Asoodeh, J Chamani
    • Year: 2017
    • Citation: Journal of Biomolecular Structure and Dynamics 35 (16), 3648-3662
  • Green synthesis of zinc oxide nanoparticles and their effect on the stability and activity of proteinase K
    • Author: MH Koupaei, B Shareghi, AA Saboury, F Davar, A Semnani, M Evini
    • Year: 2016
    • Citation: RSC advances 6 (48), 42313-42323
  • A spectroscopic and thermal stability study on the interaction between putrescine and bovine trypsin
    • Author: L Momeni, B Shareghi, AA Saboury, S Farhadian, F Reisi
    • Year: 2017
    • Citation: International journal of biological macromolecules 94, 145-153
  • Investigation the activity and stability of lysozyme on presence of magnetic nanoparticles
    • Author: B Shareghi, S Farhadian, N Zamani, M Salavati-Niasari, H Moshtaghi
    • Year: 2015
    • Citation: Journal of Industrial and Engineering Chemistry 21, 862-867
  • Catalytic activity, structure and stability of proteinase K in the presence of biosynthesized CuO nanoparticles
    • Author: M Hosseini-Koupaei, B Shareghi, AA Saboury, F Davar, VA Sirotkin
    • Year: 2019
    • Citation: International journal of biological macromolecules 122, 732-744
  • Exploring the thermal stability and activity of α-chymotrypsin in the presence of spermine
    • Author: S Farhadian, B Shareghi, AA Saboury
    • Year: 2017
    • Citation: Journal of Biomolecular Structure and Dynamics 35 (2), 435-448
  • Comparative studies on the interaction of spermidine with bovine trypsin by multispectroscopic and docking methods
    • Author: L Momeni, B Shareghi, AA Saboury, S Farhadian
    • Year: 2016
    • Citation: The Journal of Physical Chemistry B 120 (36), 9632-9641
  • Structural characterization of α‑chymotrypsin after binding to curcumin: Spectroscopic and computational analysis of their binding mechanism
    • Author: S Farhadian, B Shareghi, S Asgharzadeh, M Rajabi, H Asadi
    • Year: 2019
    • Citation: Journal of Molecular Liquids 289, 111111
  • The interaction of Naphthol Yellow S (NYS) with pepsin: Insights from spectroscopic to molecular dynamics studies
    • Author: F Hashemi-Shahraki, B Shareghi, S Farhadian
    • Year: 2020
    • Citation: International Journal of Biological Macromolecules 165, 1842-1851
  • Insights into the molecular interaction between sucrose and α-chymotrypsin
  • Author: S Farhadian, B Shareghi, L Momeni, OK Abou-Zied, VA Sirotkin
  • Year: 2018
  • Citation: International journal of biological macromolecules 114, 950-960